(19)
(11) EP 1 002 137 A1

(12)

(43) Date of publication:
24.05.2000 Bulletin 2000/21

(21) Application number: 98939218.8

(22) Date of filing: 05.08.1998
(51) International Patent Classification (IPC)7C12Q 1/70, C12Q 1/68, C12P 19/34, C12M 1/40, C07H 21/02, C07H 21/00
(86) International application number:
PCT/US9816/260
(87) International publication number:
WO 9907/899 (18.02.1999 Gazette 1999/07)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 05.08.1997 US 54788 P
18.08.1997 US 56012 P
20.08.1997 US 56500 P
09.10.1997 US 61445 P
22.10.1997 US 62690 P
03.12.1997 US 67269 P
06.01.1998 US 70572 P
06.01.1998 US 70585 P
22.07.1998 US 93844 P
04.08.1998 US 129105

(71) Applicant: TRANSGENOMIC, Inc.
San Jose, CA 95131 (US)

(72) Inventors:
  • GJERDE, Douglas, T.
    Saratoga, CA 95070 (US)
  • TAYLOR, Paul, D.
    Palo Alto, CA 94301 (US)
  • HAEFELE, Robert, M.
    Palo Alto, CA 94301 (US)

(74) Representative: Kremer, Simon Mark et al
Mewburn Ellis,York House,23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) DENATURING MULTI ION POLYNUCLEOTIDE CHROMATOGRAPHY FOR DETECTING MUTATIONS