(19)

(11)

EP 1 003 364 A1

(12)

(43) Date of publication: 31.05.2000 Bulletin 2000/22 (21) Application number: 98938178.5 (22) Date of filing: 27.07.1998

(51) International Patent Classification (IPC)7: A01H 5/00, A01H 1/00, A01H 1/04, C12N 15/05, C12N 15/09, C12N 15/11 (86) International application number: PCT/US9815/910 (87) International publication number: WO 9905/903 (11.02.1999 Gazette 1999/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 30.07.1997 US 54267 P (71) Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION Madison, WI 53705 (US)	(72) Inventors: HELGESON, John, P. Madison, WI 53711 (US) AUSTIN, Sandra Madison, WI 53711 (US) NAESS, Sara, K. Verona, WI 53593 (US) (74) Representative: Cripps, Joanna Elizabeth et al Mewburn EllisYork House23 Kingsway GB-London WC2B 6HP GB-London WC2B 6HP (GB)