(19)
(11) EP 1 003 374 A1

(12)

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 97954798.1

(22) Date of filing: 22.12.1997
(51) International Patent Classification (IPC)7A01N 43/40, A01N 43/54, A01N 43/58, C07D 401/00, C07D 401/06, C07D 401/14, A61K 31/44
(86) International application number:
PCT/US9723/888
(87) International publication number:
WO 9828/980 (09.07.1998 Gazette 1998/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 30.12.1996 US 33991 P
04.02.1997 GB 9702212

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • YOUNG, Steven, D.
    Rahway, NJ 07065 (US)
  • ANTHONY, Neville, J.
    Rahway, NJ 07065 (US)
  • GOMEZ, Robert, P.
    Rahway, NJ 07065 (US)
  • TRAN, Lekhanh, O.
    Rahway, NJ 07065 (US)

(74) Representative: Thompson, John Dr. et al
Merck & Co., Inc.European Patent DepartmentTerlings ParkEastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)


(56) References cited: : 
   
       


    (54) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE