(19)

(11)

EP 1 003 469 A2

(12)

(88) Date of publication A3: 27.11.1997 (43) Date of publication: 31.05.2000 Bulletin 2000/22 (21) Application number: 97903286.9 (22) Date of filing: 14.02.1997

(51) International Patent Classification (IPC)7: A61K 7/46, C07C 69/708, C07C 233/47, C07C 69/716 (86) International application number: PCT/EP9700/705 (87) International publication number: WO 9730/687 (28.08.1997 Gazette 1997/37)

(84) Designated Contracting States: CH DE ES FR GB IT LI NL (30) Priority: 14.02.1997 EP 96102568 (71) Applicant: GIVAUDAN-ROURE (INTERNATIONAL) S.A. 1214 Vernier, Genève (CH)	(72) Inventors: ANDERSON, Denise CH-8032 Zürich (CH) FRATER, Georg CH-8404 Winterthur (CH) GYGAX, Peter CH-8117 Fällanden (CH) (74) Representative: Buntz, Gerhard  Postfach 3255 4002 Basel 4002 Basel (CH)