(19)
(11) EP 1 003 514 A1

(12)

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 98936920.2

(22) Date of filing: 21.07.1998
(51) International Patent Classification (IPC)7: A61K 31/445, C07D 211/52, C07D 211/58, C07D 401/04, C07D 401/06, C07D 401/12, C07D 405/12, C07D 409/12, C07D 471/10
(86) International application number:
PCT/US9814/990
(87) International publication number:
WO 9904/794 (04.02.1999 Gazette 1999/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI MC NL PT SE

(30) Priority: 25.07.1997 US 53754 P
16.01.1998 GB 9800958

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • CALDWELL, Charles, G.
    Rahway, NJ 07065 (US)
  • FINKE, Paul, E.
    Rahway, NJ 07065 (US)
  • MacCOSS, Malcolm
    Rahway, NJ 07065 (US)
  • MEURER, Laura, C.
    Rahway, NJ 07065 (US)
  • MILLS, Sander, G.
    Rahway, NJ 07065 (US)
  • OATES, Bryan
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James 
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY