(19)
(11) EP 1 003 516 A1

(12)

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 99935334.5

(22) Date of filing: 18.06.1999
(51) International Patent Classification (IPC)7A61K 31/47, A61K 31/40, A61K 31/405, A61K 31/35
(86) International application number:
PCT/US9913/906
(87) International publication number:
WO 9965/493 (23.12.1999 Gazette 1999/51)
(84) Designated Contracting States:
DE FR GB NL

(30) Priority: 18.06.1998 US 89781 P

(71) Applicant: The George Washington University
Washington, D.C. 20037 (US)

(72) Inventors:
  • BOUSCAREL, Bernard
    Arlington, VA 22203 (US)
  • KOBAYASHI, Kunihiko
    Rockville, MD 20852 (US)

(74) Representative: Portal, Gérard et al
Cabinet Beau de Loménie158, rue de l'Université
75340 Paris Cédex 07
75340 Paris Cédex 07 (FR)

   


(54) METHODS OF ADMINISTERING CAMPTOTHECIN COMPOUNDS FOR THE TREATMENT OF CANCER WITH REDUCED SIDE EFFECTS