(19)

(11)

EP 1 003 527 A1

(12)

(43) Date of publication: 31.05.2000 Bulletin 2000/22 (21) Application number: 98938235.3 (22) Date of filing: 31.07.1998

(51) International Patent Classification (IPC)7: A61K 31/735, C07H 21/04, C08F 283/00, C08F 293/00, C08L 1/00, C08L 71/02 (86) International application number: PCT/US9816/012 (87) International publication number: WO 9906/055 (11.02.1999 Gazette 1999/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 01.08.1997 US 912968 30.07.1998 US  (71) Applicant: SUPRATEK PHARMA, INC. Montreal,Quebec H2Y 1M9 (CA)	(72) Inventors: KABANOV, Alexander V. Omaha, NE 68144 (US) ALAKOV, Valery, Y. D'Urfe, Quebec H9X 3B6 (CA) VINOGRADOV, Sergey, V. Omaha, NE 68117 (US) (74) Representative: Lawrence, John  Barker Brettell 138 Hagley RoadEdgbaston Birmingham B16 9PW Birmingham B16 9PW (GB)