(19)
(11) EP 1 003 734 A2

(12)

(88) Date of publication A3:
17.06.1999

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 98938234.6

(22) Date of filing: 31.07.1998
(51) International Patent Classification (IPC)7C07D 401/00
(86) International application number:
PCT/US9816/011
(87) International publication number:
WO 9907/695 (18.02.1999 Gazette 1999/07)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 05.08.1997 US 54815 P
05.08.1997 US 54902 P
16.09.1997 GB 9719706
16.09.1997 GB 9719708
24.07.1998 US 122301

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • SIDLER, Daniel, R.
    Rahway, NJ 07065 (US)
  • LARSEN, Robert, D.
    Rahway, NJ 07065 (US)
  • CHARTRAIN, Michel
    Rahway, NJ 07065 (US)
  • IKEMOTO, Norihiro
    Rahway, NJ 07065 (US)
  • ROBERGE, Christopher, M.
    Rahway, NJ 07065 (US)
  • TAYLOR, Colleen, S.
    Rahway, NJ 07065 (US)
  • LI, Wenjie
    Rahway, NJ 07065 (US)
  • BILLS, Gerald, F.
    Rahway, NJ 07065 (US)

(74) Representative: Horgan, James Michael Frederic et al
Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST