(19)
(11) EP 1 003 743 A1

(12)

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 98905975.3

(22) Date of filing: 20.01.1998
(51) International Patent Classification (IPC)7C07D 471/00, A61K 31/00
(86) International application number:
PCT/US9801/101
(87) International publication number:
WO 9831/364 (23.07.1998 Gazette 1998/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 21.01.1997 US 35854 P
14.04.1997 GB 9707490

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • MACCOSS, Malcolm
    Rahway, NJ 07065 (US)
  • MILLS, Sander, G.
    Rahway, NJ 07065 (US)
  • HARRISON, Timothy
    HarlowEssex CM20 2QR (GB)
  • SWAIN, Christopher, John
    HarlowEssex CM20 2QR (GB)

(74) Representative: Hiscock, Ian James 
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) 3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY