HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS - Patent 1003751

(19)

(11)

EP 1 003 751 A1

(12)

(43)	Date of publication:
	31.05.2000 Bulletin 2000/22

(21)	Application number: 98939182.6

(22)	Date of filing: 04.08.1998

(51)	International Patent Classification (IPC)⁷: C07D 495/04, A61K 31/44, A61K 31/55, C07D 491/048, C07D 498/04, C07D 513/04 // (C07D495/04, 333:00), C07D221:00,(C07D495/04, 333:00), C07D223:00,(C07D495/04, 333:00), C07D225:00

(86)	International application number:
	PCT/US9816/147

(87)	International publication number:
	WO 9906/410 (11.02.1999 Gazette 1999/06)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

04.08.1997 US 54753 P
03.08.1998 US 128512

(71)	Applicant: AMGEN INC.
	Thousand Oaks, CA 91320-1789 (US)

(72)	Inventors:
	THOMSON, David, S. Boulder, CO 80301 (US) KOCH, Kevin Boulder, CO 80301 (US) HWANG, Chan, Kou Boulder, CO 80304 (US) RUSSO-RODRIGUEZ, Sandra, E. Superior, CO 80027 (US) HUMMEL, Conrad Louisville, CO 80027 (US)

(74)	Representative: Richardson, Kate et al
	Forrester & Boehmert,Franz-Joseph Strasse 38 80801 München 80801 München (DE)

(54)	HYDROXAMIC ACID SUBSTITUTED FUSED HETEROCYCLIC METALLOPROTEINASE INHIBITORS