(19)
(11) EP 1 003 846 A1

(12)

(43) Date of publication:
31.05.2000 Bulletin 2000/22

(21) Application number: 98923299.6

(22) Date of filing: 06.05.1998
(51) International Patent Classification (IPC)7: C12N 9/99, C12N 9/50, A01N 43/02, A01N 43/06, A01N 43/08, A01N 43/16, A01N 43/18, C07D 307/00, C07D 307/48, C07D 309/00, C07D 319/06, C07D 321/00, C07D 333/02, C07D 333/12, C07D 333/22, C07D 335/00, C07D 335/02
(86) International application number:
PCT/US9803/200
(87) International publication number:
WO 9850/533 (12.11.1998 Gazette 1998/45)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 06.05.1997 US 45758 P

(71) Applicants:
  • Smithkline Beecham
    Philadelphia, PA 19103 (US)
  • SMITHKLINE BEECHAM PLC
    Brentford,Middlesex TW8 9BD (GB)

(72) Inventors:
  • GRIBBLE, Andrew, D.
    Herts SG3 6LR (GB)
  • FENWICK, Ashley, Edward
    Cambridgeshire SG8 6NG (GB)
  • MARQUIS, Robert, W.
    St. Davids, PA 19087 (US)
  • VEBER, Daniel, F.
    Ambler, PA 19002 (US)
  • WITHERINGTON, Jason
    Hertfordshire CM21 0BL (GB)

(74) Representative: Rutter, Keith, Dr. et al
SmithKline Beecham plcCorporate Intellectual Property,Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) PROTEASE INHIBITORS