(19)

(11)

EP 1 003 886 A1

(12)

(43) Date of publication: 31.05.2000 Bulletin 2000/22 (21) Application number: 97940681.6 (22) Date of filing: 27.08.1997

(51) International Patent Classification (IPC)7: C12N 15/67, C07K 14/39, C07K 14/035, C07K 14/47, C12N 15/62, A61K 38/18 (86) International application number: PCT/US9715/219 (87) International publication number: WO 9910/508 (04.03.1999 Gazette 1999/09)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: ARIAD GENE THERAPEUTICS, INC. Cambridge, MA 02139 (US)	(72) Inventor: SRIDARAN, Natesan Cambridge, MA 02139 (US) (74) Representative: Horner, Martin Grenville et al Cruikshank & Fairweather19 Royal Exchange Square Glasgow G1 3AEScotland Glasgow G1 3AEScotland (GB)