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EP 1 003 905 A1

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(43) Date of publication: 31.05.2000 Bulletin 2000/22 (21) Application number: 98940857.0 (22) Date of filing: 12.08.1998

(51) International Patent Classification (IPC)7: C12Q 1/00, G01N 27/327, G01N 33/543, C12Q 1/68, C12Q 1/42, C12Q 1/34, C12Q 1/44 (86) International application number: PCT/US9816/714 (87) International publication number: WO 9907/879 (18.02.1999 Gazette 1999/07)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 12.08.1997 US 55466 P 14.08.1997 US 55759 P 26.06.1998 US 105538 26.06.1998 US 105539 (71) Applicants: UNIVERSITY OF SOUTHERN CALIFORNIA Los Angeles, CA 90007-4344 (US) Fraunhofer Institut Siliziumtechnologie 25524 Itzehoe (DE)	(72) Inventors: MACPHEE, Robert, D.Univ. of Southern California Los Angeles, CA 90033 (US) TAYLOR, Clive, R.Univ. of Southern California Los Angeles, CA 90033 (US) HINTSCHE, RainerFraunhofer Institut D-25524 Itzehoe (DE) SEITZ, ReneFraunhofer Institut D-25524 Itzehoe (DE) (74) Representative: Viering, Jentschura & Partner  Postfach 22 14 43 80504 München 80504 München (DE)