(19)
(11) EP 1 005 338 A1

(12)

(43) Date of publication:
07.06.2000 Bulletin 2000/23

(21) Application number: 98937084.6

(22) Date of filing: 24.07.1998
(51) International Patent Classification (IPC)7A61K 31/34, C07D 307/78
(86) International application number:
PCT/US9815/388
(87) International publication number:
WO 9904/789 (04.02.1999 Gazette 1999/05)
(84) Designated Contracting States:
DE DK ES FR GB IT NL SE

(30) Priority: 25.07.1997 US 53742 P

(71) Applicant: PHYTERA, INC.
Worcester,Massachusetts 01605 (US)

(72) Inventors:
  • CHU, Wai-Lam, Alex
    Shrewsbury, MA 01545 (US)
  • JENSEN, Flemming, R.
    DK-2100 Copenhagen (DK)
  • JENSEN, Thomas, B.
    DK-2100 Copenhagen (DK)
  • SOEKILDE, Birgitte
    DK-3500 Vaerloese (DK)
  • SANTANA-SOERENSON, Alexandra
    DK-2820 Gentofte (DK)
  • MCALPINE, James, B.
    Bolton, MA 01740 (US)

(74) Representative: Roques, Sarah Elizabeth et al
J.A. Kemp & Co.14 South SquareGray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) SUBSTITUTED AURONE DERIVATIVES