(19)
(11) EP 1 007 063 A1

(12)

(43) Date of publication:
14.06.2000 Bulletin 2000/24

(21) Application number: 98903613.2

(22) Date of filing: 22.01.1998
(51) International Patent Classification (IPC)7A61K 35/28, C12N 5/08
(86) International application number:
PCT/US9801/112
(87) International publication number:
WO 9832/450 (30.07.1998 Gazette 1998/30)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 24.01.1997 US 36388 P

(71) Applicants:
  • Osiris Therapeutics, Inc.
    Baltimore, MD 21231-2001 (US)
  • CASE WESTERN RESERVE UNIVERSITY
    Cleveland, OH 44106-7080 (US)

(72) Inventors:
  • BRUDER, Scott, P.
    Owings Mills, MD 21117 (US)
  • CAPLAN, Arnold, I.
    Cleveland Heights, OH 44121 (US)
  • BURNS, James, S.
    Annapolis, MD 21403 (US)
  • MARSHAK, Daniel
    Lutherville, MD 21093 (US)

(74) Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH 
Postfach 3055
90014 Nürnberg
90014 Nürnberg (DE)

   


(54) BONE REGENERATION IN OSTEOPOROSIS USING HUMAN BONE MARROW MESENCHYMAL CELLS