(19)
(11)
EP 1 007 652 A1
(12)
(43)
Date of publication:
14.06.2000
Bulletin 2000/24
(21)
Application number:
98949716.9
(22)
Date of filing:
02.10.1998
(51)
International Patent Classification (IPC)
7
:
C12N
15/00
,
G01N
33/00
,
A01K
67/00
(86)
International application number:
PCT/US9820/717
(87)
International publication number:
WO 9918/191
(
15.04.1999
Gazette 1999/15)
(84)
Designated Contracting States:
AT BE CH DE DK ES FR GB IE IT LI NL SE
(30)
Priority:
02.10.1997
US 943381
(71)
Applicant:
IMCLONE SYSTEMS, INC.
New York, NY 10014 (US)
(72)
Inventors:
WITTE, Larry
Stormville, NY 12582 (US)
PYTOWSKI, Bronislaw
New York, NY 10034 (US)
BOHLEN, Peter
New York, NY 10028 (US)
SATO, Thomas
Coppell, TX 75019 (US)
(74)
Representative:
Grünecker, Kinkeldey, Stockmair & SchwanhäusserAnwaltssozietät
Maximilianstrasse 58
80538 München
80538 München (DE)
(54)
TRANSGENIC ANIMALS WITH KNOCKED-IN VEC RECEPTOR GENES AND USES THEREOF