(19)
(11) EP 1 007 723 A1

(12)

(43) Date of publication:
14.06.2000 Bulletin 2000/24

(21) Application number: 98942081.5

(22) Date of filing: 17.08.1998
(51) International Patent Classification (IPC)7C12Q 1/02, C12N 1/38, A61K 38/10
(86) International application number:
PCT/US9817/022
(87) International publication number:
WO 9909/206 (25.02.1999 Gazette 1999/08)
(84) Designated Contracting States:
DE FR GB

(30) Priority: 18.08.1997 US 56333

(71) Applicant: CENTER FOR BLOOD RESEARCH, INC.
Boston, MA 02115 (US)

(72) Inventors:
  • LIEBERMAN, Judy
    Brookline, MA 02146 (US)
  • BERESFORD, Paul, J.
    Wellesley, MA 02181 (US)

(74) Representative: Ruffles, Graham Keith et al
MARKS & CLERK,57-60 Lincoln's Inn Fields
London WC2A 3LS
London WC2A 3LS (GB)

   


(54) METHODS FOR USING GRANZYMES AND BINDING MOLECULES THEREOF FOR TREATING DISEASES CHARACTERIZED BY ABNORMAL APOPTOSIS