(19)

(11)

EP 1 011 612 A1

(12)

(43) Date of publication: 28.06.2000 Bulletin 2000/26 (21) Application number: 97943328.1 (22) Date of filing: 17.09.1997

(51) International Patent Classification (IPC)7: A61K 7/06 (86) International application number: PCT/US9716/411 (87) International publication number: WO 9913/827 (25.03.1999 Gazette 1999/12)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventor: YANG, Jian-Zhong Kobe 658 (JP) (74) Representative: Woof, Victoria et al Patent Dept.,Procter & Gamble Technical Centres Limited,Rusham Park,Whitehall Lane Egham TW20 9NW Egham TW20 9NW (GB)