(19)
(11) EP 1 014 984 A1

(12)

(43) Date of publication:
05.07.2000 Bulletin 2000/27

(21) Application number: 98943406.3

(22) Date of filing: 26.08.1998
(51) International Patent Classification (IPC)7A61K 31/495, C07D 403/06
(86) International application number:
PCT/US9817/696
(87) International publication number:
WO 9909/985 (04.03.1999 Gazette 1999/09)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 27.08.1997 US 57080 P
16.01.1998 GB 9800975

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • DINSMORE, Christopher, J.
    Rahway, NJ 07065 (US)
  • HUTCHINSON, John, H.
    Rahway, NJ 07065 (US)
  • WILLIAMS, Theresa, M.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James et al
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) INHIBITORS OF PRENYL-PROTEIN TRANSFERASE