ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY................................*JDIM360 (Ver 1.5 21 Nov 2005) - 2999001/01015577CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120061004W173deBibliographieenBibliographyfrBibliographieEP98947108.1199809112000041320040309enenen92974819970915US114119971230US2006100420064020000705200027200511232005472005051720051123NL20051123FI20060223SE20051123CH20051123LI20051123AT20051123BE20060223GR20061004200640C12N 15/10 19900101AFI19990414BHEP C12N 15/81 19900101ALI19990414BHEP deCHROMOSOMALE MUTAGENESE IN PICHIA METHANOLICAenCHROMOSOMAL MUTAGENESIS IN PICHIA METHANOLICAfrMUTAGENESE CHROMOSOMIQUE DANS PICHIA METHANOLICAWO-A-92/17595WO-A-97/17450HIEP T T ET AL: "TRANFORMATION IN THE METHYLOTROPHIC YEAST PICHIA METHANOLICA UTILIZING HOMOLOGOUS ADE1 AND HETEROLOGOUS SACCHAROMYCES CEREVISIAE ADE2 AND LEU2 GENES AS GENETIC MARKERS" YEAST, vol. 9, 1993, pages 1189-1197, XP000653248 cited in the applicationHIEP T T ET AL: "THE 5-AMINOIMIDAZOLE RIBONUCLEOTIDE-CARBOXYLASE STRUCTURAL GENE OF THE METHYLOTROPHIC YEAST PICHIA METHANOLICA: CLONING, SEQUENCING AND HOMOLOGY ANALYSIS" YEAST, vol. 9, 1993, pages 1251-1258, XP000653249RAYMOND C K ET AL: "Development of the methylotrophic yeast Pichia methanolica for the expression of the 65 kilodalton isoform of human glutamate decarboxylase." YEAST, (1998 JAN 15) 14 (1) 11-23. JOURNAL CODE: YEA. ISSN: 0749-503X., XP002090804 ENGLAND: United KingdomRAYMOND, Christopher, K.2626 N.E. 86th StreetSeattle, WA 98115USZymoGenetics, Inc.00627045APEP005561201 Eastlake Avenue EastSeattle, WA 98102USLawrence, Malcolm Grahamet al00047878HLBBshaw Merlin House Falconry Court Baker's LaneEpping, Essex CM16 5DQGBATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSEUS199801944819980911enWO199901432019990325199912