PROTEASOME INHIBITORS, UBIQUITIN PATHWAY INHIBITORS OR AGENTS THAT INTERFERE WITH THE ACTIVATION OF NF-KB VIA THE UBIQUITIN PROTEASOME PATHWAY TO TREAT INFLAMMATORY AND AUTOIMMUNE DISEASES - Patent 1017398

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EP 1 017 398 A1

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(43)	Date of publication:
	12.07.2000 Bulletin 2000/28

(21)	Application number: 98949490.1

(22)	Date of filing: 25.09.1998

(51)	International Patent Classification (IPC)⁷: A61K 31/69, A61K 31/40

(86)	International application number:
	PCT/US9820/065

(87)	International publication number:
	WO 9915/183 (01.04.1999 Gazette 1999/13)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

25.09.1997 US 61038 P
12.12.1997 US 69562 P
17.02.1998 US 74887 P

(71)	Applicant: PROSCRIPT, INC.
	Cambridge, MA 02139 (US)

(72)	Inventors:
	ELLIOT, Peter Marlborough, MA 01752 (US) ADAMS, Julian Brookline, MA 02146 (US) PLAMONDON, Louis Watertown, MA 03472-4922 (US)

(74)	Representative: Grund, Martin, Dr. et al
	Holbeinstrasse 5 81679 München 81679 München (DE)

(54)	PROTEASOME INHIBITORS, UBIQUITIN PATHWAY INHIBITORS OR AGENTS THAT INTERFERE WITH THE ACTIVATION OF NF-KB VIA THE UBIQUITIN PROTEASOME PATHWAY TO TREAT INFLAMMATORY AND AUTOIMMUNE DISEASES