(19)
(11) EP 1 017 682 A1

(12)

(43) Date of publication:
12.07.2000 Bulletin 2000/28

(21) Application number: 98948427.4

(22) Date of filing: 22.09.1998
(51) International Patent Classification (IPC)7C07D 235/08, C07D 471/04, A61K 31/435, A61K 31/415
(86) International application number:
PCT/US9819/789
(87) International publication number:
WO 9916/755 (08.04.1999 Gazette 1999/14)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 26.09.1997 US 60151 P
15.05.1998 GB 9810544

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • BILODEAU, Mark, T.
    Rahway, NJ 07065 (US)
  • HUNGATE, Randall, W.
    Rahway, NJ 07065 (US)
  • CUNNINGHAM, April, M.
    Rahway, NJ 07065 (US)
  • KOESTER, Timothy, J.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James et al
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) NOVEL ANGIOGENESIS INHIBITORS