PROCESS OF MAKING 3-ARYLOXY, 4-ARYL FURAN-2-ONES USEFUL AS INHIBITORS OF COX-2 - Patent 1017687

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EP 1 017 687 A1

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(43)	Date of publication:
	12.07.2000 Bulletin 2000/28

(21)	Application number: 98947177.6

(22)	Date of filing: 21.09.1998

(51)	International Patent Classification (IPC)⁷: C07D 307/02, C07D 405/00

(86)	International application number:
	PCT/US9819/642

(87)	International publication number:
	WO 9915/513 (01.04.1999 Gazette 1999/13)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	RO

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Priority:

24.09.1997 US 60694 P
21.07.1998 GB 9815805

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	CHEN, Cheng, Y. Rahway, NJ 07065 (US) LARSEN, Robert, D. Rahway, NJ 07065 (US) TAN, Lushi Rahway, NJ 07065 (US)

(74)	Representative: Horgan, James Michael Frederic
	Merck & Co., Inc.,Terlings Park,Eastwick Road Harlow,Essex CM20 2QR Harlow,Essex CM20 2QR (GB)

(54)	PROCESS OF MAKING 3-ARYLOXY, 4-ARYL FURAN-2-ONES USEFUL AS INHIBITORS OF COX-2