(19)
(11) EP 1 017 691 A1

(12)

(43) Date of publication:
12.07.2000 Bulletin 2000/28

(21) Application number: 98946482.1

(22) Date of filing: 24.09.1998
(51) International Patent Classification (IPC)7: C07D 407/14, C07D 413/14, C07D 401/14, C07D 215/20, A61K 31/37, A61K 31/47, A61K 31/41
(86) International application number:
PCT/FI9800/755
(87) International publication number:
WO 9915/523 (01.04.1999 Gazette 1999/13)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV MK RO SI

(30) Priority: 24.09.1997 US 937119
12.12.1997 US 990150
25.06.1998 US 104114

(71) Applicant: ORION CORPORATION (ORION-YHTYMA OY)
02200 Espoo (FI)

(72) Inventors:
  • PYSTYNEN, Jarmo
    FIN-02260 Espoo (FI)
  • TIAINEN, Eija
    FIN-02600 Espoo (FI)
  • LÖNNBERG, Kari
    FIN-08350 Routio (FI)
  • NORE, Pentti
    FIN-00100 Helsinki (FI)
  • PARHI, Seppo
    FIN-90810 Kiviniemi (FI)
  • KARJALAINEN, Arto
    FIN-02600 Espoo (FI)
  • HAIKALA, Heimo
    FIN-02180 Espoo (FI)
  • LEVIJOKI, Jouko
    FIN-00830 Helsinki (FI)

(74) Representative: Sexton, Jane Helen 
J.A. KEMP & CO.14 South SquareGray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) BISETHERS OF 1-OXA, AZA AND THIANAPHTHALEN-2-ONES AS PHOSPHOLAMBAN INHIBITORS