(19)
(11) EP 1 019 092 A1

(12)

(43) Date of publication:
19.07.2000 Bulletin 2000/29

(21) Application number: 98922382.1

(22) Date of filing: 15.05.1998
(51) International Patent Classification (IPC)7: A61K 49/00, C12N 5/06, C07H 21/04
(86) International application number:
PCT/US9810/080
(87) International publication number:
WO 9851/351 (19.11.1998 Gazette 1998/46)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 15.05.1997 US 857076
07.07.1997 US 888534

(71) Applicant: THE GENERAL HOSPITAL CORPORATION
Boston, MA 02114 (US)

(72) Inventors:
  • RUVKUN, Gary
    Newton, MA 02138 (US)
  • KIMURA, Koutarou
    Boston, MA 02114 (US)
  • PATTERSON, Garth
    Charlestown, MA 02129 (US)
  • OGG, Scott
    Newton, MA 02159 (US)
  • PARADIS, Suzanne
    Somerville, MA 02178 (US)
  • TISSENBAUM, Heidi
    Belmont, MA 02178 (US)
  • MORRIS, Jason
    New York, NY 10016 (US)
  • KOWEEK, Allison
    Somerville, MA 02178 (US)
  • PIERCE, Sarah
    Cambridge, MA 02139 (US)

(74) Representative: Bösl, Raphael, Dr. rer. nat., Dipl.-Chem. et al
Patent- und RechtsanwälteBardehle . Pagenberg . Dost . Altenburg . Geissler . IsenbruckGalileiplatz 1
81679 München
81679 München (DE)

   


(54) THERAPEUTIC AND DIAGNOSTIC TOOLS FOR IMPAIRED GLUCOSE TOLERANCE CONDITIONS