(19)

(11)

EP 1 019 121 A1

(12)

(43) Date of publication: 19.07.2000 Bulletin 2000/29 (21) Application number: 98943298.4 (22) Date of filing: 21.08.1998

(51) International Patent Classification (IPC)7: A61M 5/315 (86) International application number: PCT/US9817/374 (87) International publication number: WO 9910/032 (04.03.1999 Gazette 1999/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 22.08.1997 US 916369 11.06.1998 US 96442 (71) Applicant: COEUR LABORATORIES, INC. Raleigh, NC 27604 (US)	(72) Inventors: TRULL, Michael, Wayne Apex, NC 27502 (US) ABBOTT, Richard, L. Durham, NC 27704 (US) (74) Representative: Marchant, James Ian et al Elkington and Fife,Prospect House,8 Pembroke Road Sevenoaks,Kent TN13 1XR Sevenoaks,Kent TN13 1XR (GB)