(19)
(11) EP 1 019 382 A1

(12)

(43) Date of publication:
19.07.2000 Bulletin 2000/29

(21) Application number: 97954520.9

(22) Date of filing: 01.12.1997
(51) International Patent Classification (IPC)7C07D 235/20, A61K 31/415, C07D 401/14, C07D 403/14, C07D 413/14, C07D 413/06, C07D 471/04, C07D 498/04
(86) International application number:
PCT/US9721/849
(87) International publication number:
WO 9845/275 (15.10.1998 Gazette 1998/41)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.04.1997 US 833674

(71) Applicant: AXYS PHARMACEUTICALS, INC.
South San Francisco, CA 94080 (US)

(72) Inventors:
  • CHURCH, Timothy, J.
    Redwood City, CA 94065 (US)
  • CUTSHALL, Neil, Scott
    San Mateo, CA 94402 (US)
  • GANGLOFF, Anthony, R.
    Pacifica, CA 94044 (US)
  • JENKINS, Thomas, E.
    La Honda, CA 94020 (US)
  • LINSELL, Martin, S.
    Foster City, CA 94404 (US)
  • LITVAK, Joane
    Oakland, CA 94610 (US)
  • RICE, Kenneth, D.
    Sausalito, CA 94965 (US)
  • SPENCER, Jeffrey, R.
    San Mateo, CA 94401 (US)
  • WANG, Vivian, R.
    Redwood City, CA 94065 (US)

(74) Representative: Brasnett, Adrian Hugh et al
Mewburn EllisYork House23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH SERINE PROTEASE, PARTICULARLY TRYPTASE, ACTIVITY