(19)

(11)

EP 1 019 711 A1

(12)

(43) Date of publication: 19.07.2000 Bulletin 2000/29 (21) Application number: 97938378.3 (22) Date of filing: 18.08.1997

(51) International Patent Classification (IPC)7: G01N 27/26, G01N 27/447, C12N 15/00 (86) International application number: PCT/US9714/489 (87) International publication number: WO 9810/273 (12.03.1998 Gazette 1998/10)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 06.09.1996 US 708262 (71) Applicant: NANOGEN, INC. San Diego, CA 92121 (US)	(72) Inventors: SOSNOWSKI, Ronald, George Coronado, CA 92118 (US) BUTLER, William, Frank Carlsbad, CA 92009 (US) TU, Eugene San Diego, CA 92103 (US) NERENBERG, Michael, Irving San Diego, CA 92126 (US) HELLER, Michael, James Encinitas, CA 92024 (US) (74) Representative: Viering, Jentschura & Partner  Essener Strasse 5 46047 Oberhausen 46047 Oberhausen (DE)