(19)

(11)

EP 1 019 727 A1

(12)

(43) Date of publication: 19.07.2000 Bulletin 2000/29 (21) Application number: 98925113.7 (22) Date of filing: 02.06.1998

(51) International Patent Classification (IPC)7: G01N 33/574, C07K 16/36 (86) International application number: PCT/US9811/162 (87) International publication number: WO 9855/872 (10.12.1998 Gazette 1998/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 03.06.1997 US 48405 P 26.09.1997 US 60088 P (71) Applicant: AMDL, INC Tustin, CA 92680-7017 (US)	(72) Inventors: CRESS, Michael, C. Santa Ana, CA 92701 (US) MOORE, Ronald, J. Hermosa Beach, CA 90254 (US) NGO, That, T. Irvine, CA 92604 (US) (74) Representative: Thomas, Philip John Duval  Eric Potter Clarkson,Park View House,58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)