(19)
(11) EP 1 021 543 A1

(12)

(43) Date of publication:
26.07.2000 Bulletin 2000/30

(21) Application number: 98946598.4

(22) Date of filing: 08.10.1998
(51) International Patent Classification (IPC)7C12N 15/31, C07K 14/82, A61K 38/16
(86) International application number:
PCT/GB9803/033
(87) International publication number:
WO 9918/213 (15.04.1999 Gazette 1999/15)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 08.10.1997 GB 9721357
08.10.1997 GB 9721358
12.06.1998 GB 9812793

(71) Applicant: MEDICAL RESEARCH COUNCIL
London W1N 4AL (GB)

(72) Inventors:
  • ARKOWITZ, Robert, AlanDivision of Cell Biology
    Cambridge CB2 2QH (GB)
  • NERN, Peter, Michael, A.Division of Cell Biology
    Cambridge CB2 2QH (GB)

(74) Representative: Harding, Charles Thomas et al
D. Young & Co.21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)

   


(54) MUTANTS OF YEAST CDC24P, DEFECTIVE IN BINDING OF THE G-PROTEIN BETA SUBUNIT