(19)
(11) EP 1 023 076 A1

(12)

(43) Date of publication:
02.08.2000 Bulletin 2000/31

(21) Application number: 98908523.8

(22) Date of filing: 06.02.1998
(51) International Patent Classification (IPC)7A61K 31/70, A61K 38/17, C07H 21/04, C07K 7/00, C07K 14/00, C12N 15/12, C12Q 1/68, G01N 33/53
(86) International application number:
PCT/US9802/615
(87) International publication number:
WO 9834/624 (13.08.1998 Gazette 1998/32)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.02.1997 US 36943 P

(71) Applicants:
  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    New York,New York 10027 (US)
  • COLD SPRING HARBOR LABORATORY
    Cold Spring HarborNew York 11724 (US)

(72) Inventors:
  • PARSONS, Ramon, E.
    Manhasset, NY 11030 (US)
  • WIGLER, Michael, H.
    Cold Spring Harbor, NY 11724 (US)

(74) Representative: Lawrence, John et al
Barker Brettell 138 Hagley RoadEdgbaston
Birmingham B16 9PW
Birmingham B16 9PW (GB)

   


(54) USE OF THE P-TEN SUPPRESSOR GENE IN DIAGNOSIS AND TREATMENT OF CANCER