(19)

(11)

EP 1 027 344 A2

(12)

(88) Date of publication A3: 15.06.2000 (43) Date of publication: 16.08.2000 Bulletin 2000/33 (21) Application number: 98937641.3 (22) Date of filing: 31.07.1998

(51) International Patent Classification (IPC)7: C07D 307/86, C07C 49/755, C07D 317/64 (86) International application number: PCT/GB9802/317 (87) International publication number: WO 9906/388 (11.02.1999 Gazette 1999/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 31.07.1997 GB 9716244 (71) Applicant: PROTEOME SCIENCES PLC Cobham,Surrey KT11 3EP (GB)	(72) Inventor: ACHENBACH, Hans 65199 Wiesbaden (DE) (74) Representative: Hutchins, Michael Richard et al FRY HEATH & SPENCEThe Old College53 High Street HorleySurrey RH6 7BN HorleySurrey RH6 7BN (GB)