(19)
(11) EP 1 027 426 A1

(12)

(43) Date of publication:
16.08.2000 Bulletin 2000/33

(21) Application number: 98956229.3

(22) Date of filing: 27.10.1998
(51) International Patent Classification (IPC)7C12N 5/10
(86) International application number:
PCT/US9822/716
(87) International publication number:
WO 9923/206 (14.05.1999 Gazette 1999/19)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.10.1997 US 64448 P
03.12.1997 US 67264 P
22.12.1997 GB 9727130

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • BRAMBLE, Joye, L.
    Rahway, NJ 07065 (US)
  • SEARLES, James, A.
    Rahway, NJ 07065 (US)
  • MUZZIO, Fernando, J.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James et al
European Patent Department,Merck & Co., Inc.,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) A METHOD OF IMPROVED MIXING OF A VARICELLA-INFECTED CELL CULTURE IN ROLLER BOTTLES