(19)

(11)

EP 1 028 697 A2

(12)

(88) Date of publication A3: 12.08.1999 (43) Date of publication: 23.08.2000 Bulletin 2000/34 (21) Application number: 98939798.9 (22) Date of filing: 04.09.1998

(51) International Patent Classification (IPC)7: A61K 7/06, A61K 7/13 (86) International application number: PCT/IB9801/381 (87) International publication number: WO 9913/823 (25.03.1999 Gazette 1999/12)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE (30) Priority: 17.09.1997 WO PCT/US16/00412 17.09.1997 WO PCT/US16/00618 17.09.1997 WO PCT/US16/00615 17.09.1997 WO PCT/US16/00617 17.09.1997 WO PCT/US16/00619 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: MITSUMATSU, Arata Ashiya-shi,Hyogo 659 (JP) LUO, Xiaochun Kobe 658 (JP) UCHIYAMA, Hirotaka Kobe 658 (JP) SETSER, Julia, Leet Kobe 658 (JP) (74) Representative: Woof, Victoria et al Patent Department,Procter & Gamble Technical Centres Limited,Rusham ParkWhitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)