(19)

(11)

EP 1 030 557 A1

(12)

(43) Date of publication: 30.08.2000 Bulletin 2000/35 (21) Application number: 98950707.4 (22) Date of filing: 24.09.1998

(51) International Patent Classification (IPC)7: A01N 43/04, A01N 63/00, C12N 13/00 (86) International application number: PCT/US9820/199 (87) International publication number: WO 9917/610 (15.04.1999 Gazette 1999/15)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 02.10.1997 US 942939 (71) Applicant: The Regents of the University of California Oakland, CA 94607-5200 (US)	(72) Inventors: ROTHMAN, Stephen, S. Berkeley, CA 94708 (US) GOLDFINE, Ira, D. Kentfield, CA 94909 (US) GERMAN, Michael, S. San Francisco, CA 94122 (US) (74) Representative: Brasnett, Adrian Hugh et al Mewburn EllisYork House23 Kingsway London WC2B 6HP London WC2B 6HP (GB)