(19)

(11)

EP 1 032 354 A1

(12)

(43) Date of publication: 06.09.2000 Bulletin 2000/36 (21) Application number: 97948272.6 (22) Date of filing: 12.11.1997

(51) International Patent Classification (IPC)7: A61K 7/06, A61K 7/50 (86) International application number: PCT/US9720/735 (87) International publication number: WO 9924/004 (20.05.1999 Gazette 1999/20)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: SAKO, Takashi Kobe 658 (JP) EGOSHI, Yasuhiro Nishinomiya,Hyogo 663 (JP) (74) Representative: Woof, Victoria et al Patent Department,Procter & Gamble Technical Centres Limited,Rusham ParkWhitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)