| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
| (30) |
Priority: |
29.09.1997 US 937684
|
| (43) |
Date of publication of application: |
|
06.09.2000 Bulletin 2000/36 |
| (60) |
Divisional application: |
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07014078.5 / 1844777 |
| (73) |
Proprietor: CELGENE CORPORATION |
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Summit, NJ 07901 (US) |
|
| (72) |
Inventors: |
|
- DARIANI, Maghsoud, M.
Fanwood, NJ 07023 (US)
- ZEITLIN, Andrew, L.
Millington, NJ 07946 (US)
- ZELDIS, Jerome, B.
Princeton, NJ 08540 (US)
|
| (74) |
Representative: Hallybone, Huw George et al |
|
Carpmaels & Ransford
43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB) |
| (56) |
References cited: :
WO-A-97/03671
WO-A-97/03673
US-A- 5 733 756
|
WO-A-97/03672
WO-A-99/03471
US-A- 5 773 478
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| |
|
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- PATRICK K S ET AL: "PHARMACOLOGY OF THE ENANTIOMERS OF THREO-METHYLPHENIDATE" JOURNAL
OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, AMERICAN SOCIETY FOR PHARMACOLOGY AND,
US, vol. 241, no. 1, 1 April 1987 (1987-04-01), pages 152-158, XP000602302 ISSN: 0022-3565
- AOYAMA T ET AL: "PHARMACOKINETICS AND PHARMACODYNAMICS OF (+)-THREO-METHYLPHENIDATE
ENANTIOMER IN PATIENTS WITH HYPERSOMNIA" CLINICAL PHARMACOLOGY & THERAPEUTICS, MOSBY-YEAR
BOOK, ST LOUIS, MO, US, vol. 55, no. 3, 1 March 1994 (1994-03-01), pages 270-276,
XP000602459 ISSN: 0009-9236
- SRINIVAS, N.R., ET AL.: "Enantioselective pharmacokinetics and pharmacodynamics of
dl-threo-methylphenidate in children with attention deficit hyperactivity disorder."
CLINICAL PHARMACOLOGY AND THERAPEUTICS, vol. 52, 1992, pages 561-568, XP001073547
- ECKERMAN, D.A., ET AL.: "Enantioselective behavioral effects of threo-methylphenidate
in rats." PHARMACOLOGY BIOCHEMISTRY & BEHAVIOR, vol. 40, 1991, pages 875-880, XP001073568
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