(19)
(11) EP 1 032 707 A2

(12)

(88) Date of publication A3:
29.07.1999

(43) Date of publication:
06.09.2000 Bulletin 2000/36

(21) Application number: 98959542.6

(22) Date of filing: 20.11.1998
(51) International Patent Classification (IPC)7C12Q 1/68, C12N 9/00, C12N 15/63, C12N 15/10
(86) International application number:
PCT/US9824/854
(87) International publication number:
WO 9927/135 (03.06.1999 Gazette 1999/22)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 21.11.1997 US 976220
30.03.1998 US 79851 P

(71) Applicant: YALE UNIVERSITY
New Haven, CT 06511 (US)

(72) Inventors:
  • NILSEN, Timothy, W.
    Russell, OH 44022 (US)
  • ROBERTSON, Hugh, D.
    New York, NY 10021 (US)
  • KINDT, Thomas, J.
    Bethesda, MD 20817-2727 (US)

(74) Representative: Miles, John Stephen et al
Eric Potter Clarkson,Park View House,58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) METHOD FOR IDENTIFYING AND INHIBITING FUNCTIONAL NUCLEIC ACID MOLECULES IN CELLS