METHOD OF GENERATING CONDITIONALLY EXPRESSED MUTANT CELLS USING EXPRESSIBLE ANTISENSE SEQUENCES - Patent 1034308

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EP 1 034 308 A1

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(43)	Date of publication:
	13.09.2000 Bulletin 2000/37

(21)	Application number: 98962914.2

(22)	Date of filing: 04.12.1998

(51)	International Patent Classification (IPC)⁷: C12Q 1/68, C12N 15/64, C12N 15/74, C12N 15/75, C12N 15/76, C12N 15/77, C12N 15/78, C12N 15/79, C12N 15/81, C12N 15/85, C07H 21/02, C07H 21/04

(86)	International application number:
	PCT/US9825/808

(87)	International publication number:
	WO 9928/508 (10.06.1999 Gazette 1999/23)

(84)	Designated Contracting States:
	BE CH DE DK FR GB IT LI NL

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Priority:

04.12.1997 US 67446 P
20.04.1998 US 82534 P
21.10.1998 US 105161 P

(71)	Applicant: SMITHKLINE BEECHAM CORPORATION
	PhiladelphiaPennsylvania 19103 (US)

(72)	Inventors:
	MARRA, Andrea Collegeville, PA 19426 (US) ROSENBERG, Martin Royersford, PA 19468 (US) JI, Yinduo Spring City, PA 19475 (US)

(74)	Representative: Connell, Anthony Christopher et al
	SmithKline Beecham plcCorporate Intellectual Property,Two New Horizons Court Brentford, Middlesex TW8 9EP Brentford, Middlesex TW8 9EP (GB)

(54)	METHOD OF GENERATING CONDITIONALLY EXPRESSED MUTANT CELLS USING EXPRESSIBLE ANTISENSE SEQUENCES