(19)

(11)

EP 1 037 669 A1

(12)

(43) Date of publication: 27.09.2000 Bulletin 2000/39 (21) Application number: 98962895.3 (22) Date of filing: 11.12.1998

(51) International Patent Classification (IPC)7: A61K 48/00, A61K 35/00, C12N 15/63 (86) International application number: PCT/US9825/720 (87) International publication number: WO 9930/742 (24.06.1999 Gazette 1999/25)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 12.12.1997 US 69579 P (71) Applicants: Naldini, Luigi 10141 Torino (IT) Song, Jin-Ping Palo Alto, CA 84306 (US)	(72) Inventors: Naldini, Luigi 10141 Torino (IT) Song, Jin-Ping Palo Alto, CA 84306 (US) (74) Representative: Schüssler, Andrea, Dr. et al Kanzlei Huber & SchüsslerTruderinger Strasse 246 81825 München 81825 München (DE)