(19)
(11) EP 1 042 298 A1

(12)

(43) Date of publication:
11.10.2000 Bulletin 2000/41

(21) Application number: 98956198.0

(22) Date of filing: 29.10.1998
(51) International Patent Classification (IPC)7C07D 223/18, C07D 471/06, C07D 471/04, C07D 471/08, A61K 31/55
(86) International application number:
PCT/US9822/637
(87) International publication number:
WO 9932/453 (01.07.1999 Gazette 1999/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.12.1997 US 996422
22.06.1998 US 102726

(71) Applicants:
  • Elan Pharmaceuticals, Inc.
    South San Francisco, CA 94080 (US)
  • ELI LILLY AND COMPANY
    Indianapolis, Indiana 46227 (US)

(72) Inventors:
  • AUDIA, James, E.
    Indianapolis, IN 46278 (US)
  • MABRY, Thomas, E.
    Indianapolis, IN 46227 (US)
  • NISSEN, Jeffrey, S.
    Indianapolis, IN 46268 (US)
  • MCDANIEL, Stacey L.
    Martinsville, IN 46151 (US)

(74) Representative: Senior, Janet et al
Abel & Imray20 Red Lion Street
London WC1R 4PQ
London WC1R 4PQ (GB)

   


(54) POLYCYCLIC ALPHA-AMINO-EPSILON-CAPROLACTAMS AND RELATED COMPOUNDS