(19)
(11) EP 1 042 347 A1

(12)

(43) Date of publication:
11.10.2000 Bulletin 2000/41

(21) Application number: 98964228.5

(22) Date of filing: 22.12.1998
(51) International Patent Classification (IPC)7: C07H 21/02
(86) International application number:
PCT/US9827/310
(87) International publication number:
WO 9932/503 (01.07.1999 Gazette 1999/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 23.12.1997 US 68721 P
20.01.1998 GB 9801099

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • EVANS, Robert, K.
    Rahway, NJ 07065 (US)
  • VOLKIN, David, B.
    Rahway, NJ 07065 (US)
  • BRUNER, Mark, W.
    Rahway, NJ 07065 (US)
  • XU, Zheng
    Rahway, NJ 07065 (US)

(74) Representative: Thompson, John Dr. 
Merck & Co., Inc.European Patent DepartmentTerlings ParkEastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) DNA PHARMACEUTICAL FORMULATIONS COMPRISING CITRATE OR TRIETHANOLAMINE AND COMBINATIONS THEREOF