(19)
(11) EP 1 042 454 A1

(12)

(43) Date of publication:
11.10.2000 Bulletin 2000/41

(21) Application number: 98962294.9

(22) Date of filing: 21.12.1998
(51) International Patent Classification (IPC)7: C12N 9/00, A61K 7/28
(86) International application number:
PCT/DK9800/569
(87) International publication number:
WO 9933/957 (08.07.1999 Gazette 1999/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

(30) Priority: 29.12.1997 DK 154797

(71) Applicant: NOVO NORDISK A/S
2880 Bagsvaerd (DK)

(72) Inventors:
  • DEUSSEN, Heinz-Josef
    DK-2860 Soborg (DK)
  • FUGLSANG, Claus, Crone
    DK-2990 Niva (DK)
  • OLSEN, Arne, Agerlin
    DK-2830 Virum (DK)

   


(54) MODIFIED ENZYMES COMPRISING A POLYANIONIC DOMAIN