N-OXIDES OF HETEROCYCLIC COMPOUNDS WITH TNF AND PDE-IV INHIBITING ACTIVITY - Patent 1045845

(19)

(11)

EP 1 045 845 A1

(12)

(43)	Date of publication:
	25.10.2000 Bulletin 2000/43

(21)	Application number: 99954132.9

(22)	Date of filing: 02.11.1999

(51)	International Patent Classification (IPC)⁷: C07D 401/12, A61K 31/47, A61P 11/06

(86)	International application number:
	PCT/GB9903/628

(87)	International publication number:
	WO 0026/208 (11.05.2000 Gazette 2000/19)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

04.11.1998 GB 9824160

(71)	Applicant: Darwin Discovery Limited
	Cambridge CB4 4WE (GB)

(72)	Inventors:
	DYKE, Hazel Joan,Darwin Discovery Limited Cambridge CB4 4WE (GB) MONTANA, John Gary,Darwin Discovery Limited Cambridge CB4 4WE (GB)

(74)	Representative: Perry, Robert Edward
	GILL JENNINGS & EVERYBroadgate House7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)

(54)	N-OXIDES OF HETEROCYCLIC COMPOUNDS WITH TNF AND PDE-IV INHIBITING ACTIVITY