(19)
(11) EP 1 045 908 A2

(12)

(88) Date of publication A3:
30.09.1999

(43) Date of publication:
25.10.2000 Bulletin 2000/43

(21) Application number: 99902140.5

(22) Date of filing: 08.01.1999
(51) International Patent Classification (IPC)7C12N 15/16, C07K 14/575, C07K 16/26, A61K 48/00, A61K 38/22, C12Q 1/68, G01N 33/68, C12N 15/11
(86) International application number:
PCT/US9900/489
(87) International publication number:
WO 9935/266 (15.07.1999 Gazette 1999/28)
(84) Designated Contracting States:
BE CH DE DK FR GB IT LI NL

(30) Priority: 09.01.1998 US 72383 P
04.02.1998 US 73616 P
20.02.1998 US 27381
05.01.1999 US 225747

(71) Applicants:
  • SMITHKLINE BEECHAM CORPORATION
    PhiladelphiaPennsylvania 19103 (US)
  • SMITHKLINE BEECHAM PLC
    Brentford,Middlesex TW8 9EP (GB)
  • Smithkline BeechamLaboratoires Pharmaceutiques
    35762 Saint GrĂ©goire Cedex (FR)

(72) Inventors:
  • CULP, Jeffrey, S.
    Collegeville, PA 19426 (US)
  • MCNULTY, Dean, E.
    Philadelphia, PA 19147 (US)
  • ELLIS, Catherine, E.
    Glassboro, NJ 08028 (US)
  • DOUGLAS, Stephen, A.,B202 La Maison Apartments
    Wayne, PA 19087 (US)
  • WILLETTE, Robert, N.
    Pottstown, PA 19464 (US)
  • AIYAR, Nambi, V.
    Berywn, PA 19312 (US)
  • ARNOLD, Anne, Romanic
    Wynnewood, PA 19097 (US)
  • KHANDOUDI, Nassirah
    F-35760 Saint-GrĂ©goire (FR)
  • GOUT, Bernard
    F-35000 Rennes (FR)
  • AL-BARAZANJI, Kamal
    Bishops Stortford,Herts CM23 4DX (GB)

(74) Representative: Crump, Julian Richard John 
FJ Cleveland,40-43 Chancery Lane
London WC2A 1JQ
London WC2A 1JQ (GB)

   


(54) HUMAN UROTENSIN II