(19)
(11) EP 1 045 919 A1

(12)

(43) Date of publication:
25.10.2000 Bulletin 2000/43

(21) Application number: 99902292.4

(22) Date of filing: 15.01.1999
(51) International Patent Classification (IPC)7: C12N 15/85, C12N 15/86, C12N 15/12, A61K 48/00
(86) International application number:
PCT/US9900/915
(87) International publication number:
WO 9936/557 (22.07.1999 Gazette 1999/29)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 16.01.1998 US 71673

(71) Applicant: GENZYME CORPORATION
Framingham,Massachusetts 01701 (US)

(72) Inventors:
  • ARMENTANO, Donna
    Belmont, MA 02718 (US)
  • YEW, Nelson
    West Upton, MA 01568 (US)
  • MARSHALL, John
    Hopedale, MA 01747 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) NOVEL PROMOTER ELEMENTS FOR PERSISTENT GENE EXPRESSION