(19)
(11) EP 1 047 698 A1

(12)

(43) Date of publication:
02.11.2000 Bulletin 2000/44

(21) Application number: 99901277.6

(22) Date of filing: 11.01.1999
(51) International Patent Classification (IPC)7: C07D 487/08, C07D 471/08
// (A61K31/44, 31:40),(C07D487/08, 209:00), C07D209:00,(C07D471/08, 241:00), C07D221:00,(C07D471/08, 221:00), C07D209:00,(C07D471/08, 221:00), C07D221:00
(86) International application number:
PCT/US9900/046
(87) International publication number:
WO 9936/424 (22.07.1999 Gazette 1999/29)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
LT LV RO

(30) Priority: 14.01.1998 US 6942

(71) Applicant: SCHERING CORPORATION
KenilworthNew Jersey 07033 (US)

(72) Inventors:
  • SHUE, Ho-Jane
    Pine Brook, NJ 07058 (US)
  • SHIH, Neng-Yang
    North Caldwell, NJ 07006 (US)
  • BLYTHIN, David, J.
    North Caldwell, NJ 07006 (US)
  • CHEN, Xiao
    Edison, NJ 08820 (US)
  • PIWINSKI, John, J.
    Lebanon, NJ 08833 (US)
  • MCCORMICK, Kevin, D.
    Edison, NJ 08820 (US)

(74) Representative: Ritter, Stephen David et al
Mathys & Squire100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) PIPERAZINO DERIVATIVES AS NEUROKININ ANTAGONISTS