AN AUTOREGULATORY SYSTEM FOR VALIDATING MICROBIAL GENES AS POSSIBLE ANTIMICROBIAL TARGETS USING A TETRACYCLINE-CONTROLLABLE ELEMENT - Patent 1049789

(19)

(11)

EP 1 049 789 A1

(12)

(43)	Date of publication:
	08.11.2000 Bulletin 2000/45

(21)	Application number: 99903005.9

(22)	Date of filing: 12.01.1999

(51)	International Patent Classification (IPC)⁷: C12N 15/63, C12N 15/90, C12Q 1/68, C12Q 1/04

(86)	International application number:
	PCT/US9900/371

(87)	International publication number:
	WO 9936/554 (22.07.1999 Gazette 1999/29)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

(30)

Priority:

16.01.1998 US 71640 P

(71)	Applicant: PHARMACIA & UPJOHN COMPANY
	Kalamazoo,Michigan 49001 (US)

(72)	Inventors:
	QUINN, Cheryl, L. Kalamazoo, MI 49008 (US) FORD, Charles, W. Portage, MI 49024 (US)

(74)	Representative: Perry, Robert Edward et al
	GILL JENNINGS & EVERYBroadgate House7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)

(54)	AN AUTOREGULATORY SYSTEM FOR VALIDATING MICROBIAL GENES AS POSSIBLE ANTIMICROBIAL TARGETS USING A TETRACYCLINE-CONTROLLABLE ELEMENT