2,3,4,5-TETRAHYDRO-1H-[1,4]-BENZODIAZEPINE-3-HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS - Patent 1051407

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EP 1 051 407 A1

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(43)	Date of publication:
	15.11.2000 Bulletin 2000/46

(21)	Application number: 99902417.7

(22)	Date of filing: 22.01.1999

(51)	International Patent Classification (IPC)⁷: C07D 243/14, A61K 31/395, C07D 401/06, C07D 409/06, C07D 405/06, C07D 403/10

(86)	International application number:
	PCT/US9901/325

(87)	International publication number:
	WO 9937/625 (29.07.1999 Gazette 1999/30)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	AL LT LV RO SI

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Priority:

27.01.1998 US 14374

(71)	Applicant: American Cyanamid Company
	Madison,New Jersey 07940-0874 (US)

(72)	Inventors:
	ALBRIGHT, Jay, Donald Nanuet, NY 10954 (US) DELOS SANTOS, Efren, Guillermo Nanuet, NY 10954 (US) DU, Xuemei Valley Cottage, NY 10989 (US)

(74)	Representative: Talbott, Dawn Jacqueline et al
	Wyeth Laboratories,Patent Department,Huntercombe Lane South,Taplow Maidenhead,Berkshire SL6 0PH Maidenhead,Berkshire SL6 0PH (GB)

(54)	2,3,4,5-TETRAHYDRO-1H-[1,4]-BENZODIAZEPINE-3-HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS