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(11)

EP 1 053 230 A1

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(43) Date of publication: 22.11.2000 Bulletin 2000/47 (21) Application number: 99902309.6 (22) Date of filing: 13.01.1999

(51) International Patent Classification (IPC)7: C07D 251/66, C07D 251/70, A61K 31/53, C07D 403/12, C07D 405/12, C07D 409/12 (86) International application number: PCT/US9900/945 (87) International publication number: WO 9936/410 (22.07.1999 Gazette 1999/29)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 13.01.1998 US 6430 (71) Applicant: Scriptgen Pharmaceuticals, Inc. Waltham, MA 02154 (US)	(72) Inventors: ARENAS, Jaime, E. Lexington, MA 02173 (US) CLOAD, Sharon, T. Cambridge, MA 02138 (US) FLEMING, Elizabeth, S. Belmont, MA 02178 (US) XIANG, Yi, Bin Acton, MA 01720 (US) (74) Representative: Wetke, Ellen et al Hofman-Bang A/SHans Bekkevolds Allé 7 2900 Hellerup 2900 Hellerup (DK)